Making metabolism more inefficient can reduce obesity

Friday, October 3, 2008 - 10:21 in Health & Medicine

In a discovery that counters prevailing thought, a study in mice has found that inactivating a pair of key genes involved in "fat-burning" can actually increase energy expenditure and help lower diet-induced obesity. These unusual findings, appearing this week in the JBC, might lead to some new roads in weight-loss therapy.

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