Greater response to placebo in children than in adults

In a systematic review of antiepileptic drugs, Philippe Ryvlin (of the Hospices Civils de Lyon, France) and colleagues show that children with drug-resistant partial epilepsy enrolled in trials seem to have a greater response to placebo than adults enrolled in such trials. This finding is an important factor to consider when designing drug trials to be carried out in children with epilepsy.

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