Study Suggests Breakthrough in Controlling T Cell Activation
Tuesday, May 13, 2014 - 05:50
in Health & Medicine
The discovery of a crucial mechanism that controls the activation of T cells, a blood cell whose primary job is to fight infection in the body, may enable the development of new drugs to treat autoimmune disease, transplant rejection, and similar disorders in which T cells play a major role. The finding, "T Cell Receptor Signals to NF-kB Are Transmitted by a Cytosolic p62-Bcl10-Malt1-IKK Signalosome," was published in the May 13 issue of Science Signaling.