Studies target amyloid plaques and tau tangles

For a long time now, scientists studying treatments for Alzheimer's disease have focused on telltale plaques that appear in patients' diseased brains as a target for therapy. The plaques are clumps of a small protein called beta-amyloid that build up in the space around nerve cells and interfere with normal brain function. Thus, the thinking goes, if plaques can be prevented from forming or cleared with medicine, the disease could be slowed.

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