New protein identified in bacterial arsenal

Virulence factors evolved nearly a billion years ago as opportunistic agents injected by bacteria to hijack the machinery of infected cells. Researchers at The Rockefeller University have discovered the molecular makeup of one such factor used by Salmonella — a ubiquitin ligase — that appears to take over a key process that regulates a wide range of cellular duties, from cell-cycle progression to cell death and even communication between cells.

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