Beta Secretase Inhibitors For Alzheimer's Disease

Sunday, April 5, 2015 - 15:40 in Health & Medicine

With each new amyloid-targeting treatment for Alzheimer's disease that has been developed, there has been a corresponding concern about antibodies targeting amyloid-β peptide (Aβ) producing inflammation in the brain in some patients. Gamma secretase inhibitors tend to produce adverse effects by interacting with Notch, an important pathway for cellular signaling.  read more

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