Common Genetic Architectures Of Down Syndrome

Trisomy 21, commonly called Down syndrome, is a genetic condition in which a person has 47 chromosomes instead of the usual 46 - three of the #21 chromosomes, rather than the usual two.(1)  Down syndrome  is one of the most common genetic birth defects, affecting approximately one in 800 to 1,000 babies, and includes a combination of mental retardation, characteristic facial features and, often, heart defects, visual and hearing impairment, and other health problems.  It is very often accompanied by pathologies found in the general population: Alzheimer's disease, leukemia, or cardiac deficiency.  read more

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