Persistent DNA damage in the placenta affects pregnancy outcomes

Tuesday, June 16, 2020 - 18:00 in Biology & Nature

Scientists have shown that a dysfunctional placenta can play a previously unrecognized role during the earliest stages of development in mouse models of Cornelia de Lange syndrome. People with this rare genetic disorder often harbor mutations in cohesins, ring-like proteins that help DNA organize and repair itself.

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