First all-human mouse model of inherited prion disease
Wednesday, June 10, 2020 - 11:43
in Biology & Nature
Human prion diseases include Creutzfeldt-Jakob disease (CJD) and Gerstmann-Sträussler-Scheinker disease (GSS). A new study reports a significant advance in the development of mouse models of human prion diseases. The study demonstrates spontaneous formation of disease-relevant, transmissible prion protein assemblies in mice bearing only human forms of the prion protein.