Healthy blood stem cells have as many DNA mutations as leukemic cells
Wednesday, November 28, 2018 - 21:00
in Biology & Nature
Researchers have shown that the number of mutations in healthy and leukemic blood stem cells does not differ. Rather the location of the mutations in the DNA is relevant. Using the mutation patterns in the hematopoietic stem and progenitor cells (HSPCs) the team was able to trace the developmental lineage tree of the cells.