Blocking known cancer driver unexpectedly reveals a new tumor-promoting pathway
Tuesday, May 17, 2016 - 16:20
in Health & Medicine
While investigating a potential therapeutic target for the ERK1 and 2 pathway, a widely expressed signaling molecule known to drive cancer growth in one third of patients with colorectal cancer, researchers found that an alternative pathway immediately emerges when ERK1/2 is halted, thus allowing tumor cell proliferation to continue.