Targeted next-generation sequencing reveals a high number of genomic mutations in advanced malignant
Thursday, December 18, 2014 - 02:30
in Biology & Nature
Next generation sequencing in malignant pleural mesothelioma tumors shows a complex mutational setting with a high number of genetic alterations in genes involved in DNA repair, cell survival and cell proliferation pathways. Increased accumulation of mutations correlates with early progression of the tumor and decreased survival.