Protein ZEB1 promotes breast tumor resistance to radiation therapy

Monday, August 4, 2014 - 10:30 in Health & Medicine

One protein with the even more out-there name of ZEB1 (zinc finger E-box binding homeobox 1), is now thought to keep breast cancer cells from being successfully treated with radiation therapy, researchers report. ZEB1 may actually be helping breast tumor cells repair DNA damage caused by radiation treatment by ramping up a first-line of defense known as DNA damage response pathway, they say.

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