Leukemia cells exploit 'enhancer' DNA elements to cause lethal disease

A team of researchers has identified a leukemia-specific stretch of DNA called an enhancer element that enables cancerous blood cells to proliferate in acute myeloid leukemia, a devastating cancer that is incurable in 70 percent of patients. Just as important, the findings offer a mechanistic insight into how a new class of promising drugs -- one version of which is already in human clinical trials -- appears to halt the growth of cancer cells so effectively.

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