Two-week treatment found to prevent epilepsy in mice gives hope for drug development

Temporal lobe epilepsy is characterized by recurrent seizures throughout life and often behavioral abnormalities, with devastating impacts on patients and their families. Unfortunately, the condition is often not responsive to anticonvulsants. Now scientists report that targeting a particular signaling pathway in mice can prevent the development of temporal lobe epilepsy with two weeks of treatment, offering hope that researchers will be able to develop effective drugs to mitigate recurrent seizures and the development of epilepsy.

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