Shutting down DNA construction: How senescence halts growth of potential cancers
Thursday, April 4, 2013 - 20:30
in Health & Medicine
How does oncogene-induced senescence work? Imagine the cell as a construction site where work continues as long as bricks (nucleotides) are available. When an oncogene is damaged, it is like hiring excess workers and cancelling orders for bricks. When brick supplies run out, construction ends and the cell becomes senescent.