Shedding light on early Parkinson's disease pathology
Monday, April 1, 2013 - 11:00
in Biology & Nature
In a mouse model of early Parkinson's disease (PD), animals displayed movement deficits, loss of tyrosine-hydroxylase (TH)-positive fibers in the striatum, and astro-gliosis and micro-gliosis in the substantia nigra (SN), without the loss of nigral dopaminergic neurons. The findings may cast light on the molecular processes involved in the initial stages of PD.