In fight against cancer, a closer look at nuclear blebbing

Tuesday, February 19, 2013 - 20:00 in Health & Medicine

Misshapen cell nuclei are frequently observed in the cells of people with cancer and other diseases, but what causes the abnormality -- and why it is associated with certain disorders -- has remained unclear. Researchers have now developed a mathematical model that clarifies the mechanisms that cause bulges known as "blebs" in cells' nuclear membranes. The work could be a step toward bleb prevention, which may ultimately provide potential therapies for related diseases.

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