New strategy for interfering with potent cancer-causing gene
Monday, February 11, 2013 - 18:00
in Health & Medicine
About five-ten percent of cases of acute myeloid leukemia, an aggressive blood cancer that is currently incurable in 70 percent of patients, are characterized by the rearrangement of a gene called MLL (Mixed-Lineage Leukemia). Medical researchers have identified a protein, RNF20, involved in DNA packaging that is essential for MLL-rearranged leukemia and thus presents an attractive therapeutic target.