Novel role of BRCA1 in regulating the survival of skin stem cells identified
Thursday, December 27, 2012 - 09:00
in Health & Medicine
Researchers have uncovered a novel role of BRCA1 in regulating the survival of skin stem cells. Our DNA, which stores our genetic information, is constantly submitted to damage. If not properly repaired, DNA damage can lead to cell death, which may in turn lead to tissue exhaustion and aging, or induce mutations resulting in uncontrolled cell proliferation and cancer. In this study scientists showed the critical role of Brca1 for the maintenance of hair follicle stem cells.