Fluorescent biosensor to aid in drug development

Scientists have developed a new fluorescent biosensor that could aid in the development of an important class of drugs that target a crucial class of proteins called G protein-coupled receptors (GPCRs). GPCRs are popular drug targets because of the pivotal role they play in cells' communication circuits responsible for regulating functions critical to health, including circuits involved in heart and lung function, mood, cognition and memory, digestion and the inflammatory response.

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