... of iron uptake system of Mycobacterium tuberculosis, which is considered to be one of the important drug targets.
Iron acquisition and regulation in intracellular pathogens especially mycobacterium ...
... the test tube, so it has been overlooked as a candidate drug target," says Dr. Carl F. Nathan, ... . Ehrt. "This is an example of a new class of potential targets for anti-infective agents," continues Dr. ...
... -binding results in pro-inflammatory signals. We have to continue to better understand the integrin signaling process if we are to find more potential drug targets for the treatment of inflammation."
... a new advance in the study of major diabetes drug target. The advance - described by the researchers as 'very ... , PPAR gamma. PPAR gamma is a major drug target for the treatment of type 2 diabetes. ...
... of Leicester have published findings about a new advance in the study of major diabetes drug target. The advance - described by the researchers as 'very significant' - could lead to new drugs being ...
... -in-Chief of The FASEB Journal, "but this could be a major advance for physicians looking for a safe drug target in their search to keep obese patients healthy while their weight becomes normal."
... Cancer Center have discovered what could be a novel drug target for an often difficult-to-treat form ... phase.
The researchers are planning to screen potential drugs to treat CLL based on the PDE7B-cAMP ...
... of gallstones and certain rare forms of diabetes.
"Each of these genes is a potentially interesting drug target," said Abecasis. Statins, a class of cholesterol lowering drugs used to reduce the risk ...
... of Oxford in England and the University of British Columbia in Canada report a binding pocket in a previously implicated gene that may be an attractive research prospect as a potential drug target.
... a blueprint for strategies to block a new anti-mycobacterial target," Kiessling says.
New drug targets will be critical in the fight against tuberculosis, as drug-resistant strains are becoming ...
... 's authors. "But levels were highest in aggressive types, making Met a promising drug target that could help patients that currently have few treatment options."
According to the American Cancer ...
... , but then deemed undruggable, more attractive. Protein-protein interactions have been researched as drug targets against a range of diseases, from certain cancers to neurodegenerative diseases. This ...
... played a role in alcohol consumption, but now, we actually know some of the genes that are involved. As a result of this work, we have a potential drug target for curing this insidious condition."
... .”
“We are excited about the success of this work and the prospects it holds for future drug development,” said USAMRIID principal investigator S. Ashraf Ahmed, who initiated the structure-based ...
... including tarenflurbil, work this way," Dr. Kukar says. "This is one of the few examples of a small molecule drug that targets a protein substrate rather than the enzyme that works on it, and from a ...
