Innate immune mechanisms can control disease progression in HIV-positive patients

A new study by researchers in Spain shows that dendritic cells in HIV positive patients who spontaneously control the infection produce high levels of alpha-defensins. Results show that cells from these patients produce higher levels of alpha-defensins than the non-infected ones. This reveals a better control of HIV and slower disease progression. The study of patients, especially elite controllers, is relevant since these individuals demonstrate that natural control of HIV without therapy is possible.

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