Mouse Model Of Parkinson's Reproduces Nonmotor Symptoms

Tuesday, June 23, 2009 - 09:14 in Health & Medicine

Nonmotor symptoms of Parkinson's include digestive and sleep problems, loss of sense of smell and depression. A mouse with a mutation in a gene responsible for packaging neurotransmitters like dopamine and norepinephrine reproduces the major non-motor symptoms as well as motor symptoms. The finding sheds light on nonmotor symptoms' causes and their relationship with the neurodegeneration seen in Parkinson's.

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