Breaking BubR1 Mimics Genetic Shuffle Seen In Cancer Cells
Thursday, November 27, 2008 - 01:44
in Biology & Nature
A study of how BubR1 helps make sure chromosomes are equally distributed during mitosis might explain how the process of cell division goes so awry in cancer, according to researchers. Mutations in BubR1 lead to a genetic rearrangement similar to a process that allows cancer cells to evade destruction by medical treatment. Inhibiting BubR1 could be a strategy that enhances the killing power of current therapeutics.