Why Treatment Isn't Effective For HIV

Wednesday, August 6, 2008 - 23:28 in Health & Medicine

Researchers have answered a key question as to why antiretroviral therapy isn't effective in restoring immunity in HIV-infected patients. Once a person is infected with the virus, fibrosis, or scarring, occurs in the lymph nodes -- the home of T cells that fight infection. And once fibrosis occurs, T cells can't repopulate the lymph nodes when HIV therapy begins, according to a professor of medicine and principal investigator on the study.

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