Gene Function In Regulating Body Size Helps Inform Novel Cancer Treatments

Monday, May 12, 2008 - 19:21 in Health & Medicine

In a leading study that has implications for the development of novel therapies for a number of breast, lung and ovarian cancers that have lost the expression of a gene called glypican-3, researchers have discovered how the loss of the GPC3 gene induces overgrowth through certain growth factors such as Sonic Hedgehog which stimulate cancer growth.

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