Chromosome 'Lassoing': A New Key Mechanism In Cell Division

Saturday, May 10, 2008 - 17:28 in Biology & Nature

Scientists have revealed the function of a protein that is indispensable for passing on an accurate copy of the genome from mother to daughter cells. This study opens up new avenues of research to reduce the toxicity of chemotherapy in the treatment of cancer. The protein can be compared to a cowboy's lasso: it catches chromosomes and ties them to a transitory structure assembled during cell division. Once they have been neatly tied up, the chromosomes await the end of replication to be equally distributed between the two daughter cells.

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