Salk scientists detect molecular obesity link to insulin resistance, type 2 diabetes
Wednesday, March 4, 2009 - 06:28
in Health & Medicine
A molecular switch found in the fat tissue of obese mice is a critical factor in the development of insulin resistance, report scientists at the Salk Institute for Biological Studies. Previously found to increase glucose production by the liver during fasting, the culprit - a protein known as CREB - is also activated in fat tissue of obese mice where it promotes insulin resistance...