Salk scientists detect molecular obesity link to insulin resistance, type 2 diabetes

Wednesday, March 4, 2009 - 06:28 in Health & Medicine

A molecular switch found in the fat tissue of obese mice is a critical factor in the development of insulin resistance, report scientists at the Salk Institute for Biological Studies. Previously found to increase glucose production by the liver during fasting, the culprit - a protein known as CREB - is also activated in fat tissue of obese mice where it promotes insulin resistance...

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