Alzheimer’s gene triggers early breakdowns in blood-brain barrier, predicting cognitive decline

Thursday, April 30, 2020 - 17:30 in Biology & Nature

New USC research reveals how APOE4 — a genetic culprit for Alzheimer’s disease — triggers leaks in the brain’s plumbing system, allowing toxic substances to seep into the brain areas responsible for memory encoding and other cognitive functions. The damage is linked to future problems in learning and memory, even when the disease’s signature sticky […]

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