Unmuting large silent genes lets bacteria produce new molecules, potential drug candidates

Wednesday, January 2, 2019 - 10:50 in Biology & Nature

By enticing away the repressors dampening unexpressed, silent genes in Streptomyces bacteria, researchers at the University of Illinois have unlocked several large gene clusters for new natural products, according to a study published in the journal Nature Chemical Biology. Since many antibiotics, anti-cancer agents and other drugs have been derived from genes readily expressed in Streptomyces, […]

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