FLCN haploinsufficiency leads to lung fibroblast dysfunction in patients with BHD syndrome
Friday, November 25, 2016 - 08:01
in Health & Medicine
Birt–Hogg–Dubé syndrome (BHD) is caused by germline mutations in the FLCN gene and characterized by fibrofolliculomas, lung cysts, spontaneous pneumothorax and renal tumours. The stretch hypothesis for pulmonary cyst formation proposes that cysts in BHD arise from ... Read more