Split RNA switch system boosts precision of cell-specific gene expression control

Thursday, July 3, 2025 - 11:08 in Biology & Nature

Professor Hirohide Saito (Department of Life Science Frontiers at CiRA / The University of Tokyo) and Assistant Professor Hirohisa Ohno (Department of Life Science Frontiers at CiRA) recently led a team effort to develop a novel RNA-based system called the split RNA switch, integrating translational and post-translational control to achieve highly specific gene expression in targeted cell types. Their study is published in Nature Communications.

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