Fine-tuning metabolic gene expression to identify variants in yeast genes

Scientists have developed a more nuanced library approach to tuning gene expression in metabolic pathways. Compared to the traditional way, which leverages an all-or-nothing approach to expression, scientists can now opt for various shades of gray. The ability to fine-tune the level of gene expression allowed researchers to identify variations of essential genes in metabolic networks that were missed using traditional approaches.

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