Analyzing chromatin status of poised genes may provide powerful tool to predict transcription potential
Wednesday, July 29, 2020 - 08:00
in Biology & Nature
In eukaryotic cells, the genomic DNA is hierarchically packaged by histones into chromatin. Chromatin structure and its plasticity play an important role in the activation and silencing of gene transcription, and determine the cell fate during differentiation and development. Therefore, it is an important issue for scientific frontier to study the chromatin status and transcription potentials of the key development genes during the cell differentiation.