S-glutathionylation of human-inducible Hsp70 reveals regulatory mechanism involving C-terminal α-helical lid
Monday, July 27, 2020 - 10:30
in Biology & Nature
Heat shock protein 70 (Hsp70) proteins are a family of ancient and conserved molecular chaperones. They play an essential role in maintaining protein homeostasis, including facilitating protein folding and degradation, preventing protein aggregation, and participating in the stress response. Disruption of the cellular quality control machinery is associated with aging, cancer and neurodegenerative diseases.