Structural insights into Fe-S protein biogenesis
Monday, July 6, 2020 - 10:00
in Biology & Nature
The cytosolic iron sulfur assembly (CIA) pathway is required for the insertion of Fe-S clusters into proteins, including many DNA replication and repair factors. Despite its essential cellular function, this pathway remains enigmatic. A new integrative structural and biochemical study from the Thomä group now provides detailed insights into the mechanisms of Fe-S protein biogenesis.