Novel switch protein that 'turns on' sperm for fertilization

Thursday, June 4, 2020 - 13:12 in Biology & Nature

For a sperm to fertilize an egg, the sperm must first mature in a man's epididymis. Now, an international team of researchers has identified a chain of events in which a protein secreted by the testis travels in the luminal fluid, binds to a receptor on the epididymis to induce its differentiation and secretion of a second protein that matures the sperm and enables each sperm to be motile in females.

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