New microscopy method provides unprecedented look at amyloid protein structure

Thursday, June 4, 2020 - 09:11 in Biology & Nature

Neurodegenerative diseases such as Alzheimer's and Parkinson's are often accompanied by amyloid proteins in the brain that have become clumped or misfolded. A newly developed technique that measures the orientation of single molecules is enabling optical microscopy to be used, for the first time, to reveal nanoscale details about the structures of these problematic proteins.

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