Well begun is half done? Researchers study the recipe for efficient protein synthesis
Thursday, May 28, 2020 - 08:50
in Biology & Nature
Skoltech scientists and their colleagues have studied more than 30 thousand variants of genetic sequences encoding two fluorescent proteins in order to determine which characteristics of mRNA and of the first dozen or so codons in it can increase the efficiency of translation. Among other things, they found that rare codons at the beginning of the sequence do not seem to enhance translation, contrary to some hypotheses. The paper was published in the journal Nucleic Acids Research.