RDE-3 found to add pUG tails to targets of RNA interference and to transposon RNAs

Monday, May 25, 2020 - 09:30 in Biology & Nature

A team of researchers from Harvard Medical School, Nanjing Agricultural University and the University of Wisconsin has found that the protein RDE-3 in nematode worms adds pUG tails to targets of RNA interference and transposon RNAs. In their paper published in the journal Nature, the group describe their findings and the ways their work could impact the study of gene silencing through generations. Kailee Reed and Taiowa Montgomery with Colorado State University have published a News and Views piece outlining the work by the team in China and suggest that the team's finding could pave the way for research into whether poly(UG)-tailed RNAs serve the same role in other species.

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