First simulation of a full-sized mitochondrial membrane
Friday, May 8, 2020 - 08:30
in Biology & Nature
Scientists from the University of Groningen have developed a method that combines different resolution levels in a computer simulation of biological membranes. Their algorithm backmaps a large-scale model that includes features such as membrane curvature to its corresponding coarse-grained molecular model. This has allowed them to zoom in on toxin-induced membrane budding and to simulate a full-sized mitochondrial lipid membrane. Their approach, which was published in the journal Nature Communications on 8 May, opens the way to whole-cell simulations at a molecular level.