Researchers identify the binding model of Congo Red dye to amyloid fibrils
Friday, May 1, 2020 - 09:31
in Biology & Nature
The aggregation of proteins in amyloid structure, a process described in mammals and fungus and bacteria, is implied in about 36 human diseases, including Alzheimer's disease, Parkinson's disease and type 2 diabetes. Most of the amyloid fibres are known for their ability to bind Congo-red, regarded a specific marker of amyloid structures. This adds a great value to the compound Congo-Red, since it is one of the most used to detect the presence of amyloids and characterize the process of aggregation involved in amyloidogenic diseases.