Uncovering novel relationships between SLCs and cytotoxic drugs in human cells
Tuesday, March 10, 2020 - 07:00
in Biology & Nature
CeMM Researchers have studied how solute carriers (SLCs), a large family of membrane transport proteins, influence the activity and potency of cytotoxic drugs. Their study in Nature Chemical Biology uncovers the dependency of most drugs studied on the function of at least one SLC. These findings shed new light on the biological roles of transporters, and open a path to the development of future precision therapies.