How do protein tangles get so long in Alzheimer's?
Monday, February 11, 2019 - 13:20
in Health & Medicine
Early in the course of Alzheimer's disease—long before future patients begin to notice symptoms—neurofibrillary tangles composed of tau protein aggregates begin to form in their brain cells. How toxic these aggregates are and how well they spread depend on their size. However, scientists studying tangle formation have not been able to explain why different sizes of cable-like tau aggregates appear in disease.