DNA in regions far from target genes governs cell state transitions through a coordinated wave of regulatory activity

Friday, March 20, 2015 - 10:00 in Biology & Nature

By comparing RNA expression patterns across many different tissues and time points, an international research team led by RIKEN scientists has discovered some basic rules of biological regulation. The findings, obtained by mapping the sequence of gene activation when cells undergo a state change, could pave the way for regenerative therapies that modulate cell fate.

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