Coenzyme A plays leading role in nitric oxide function so essential to cell metabolism
Wednesday, January 14, 2015 - 15:20
in Biology & Nature
Case Western Reserve and University Hospitals (UH) Case Medical Center researchers and physicians have discovered that the molecule known as coenzyme A plays a key role in cell metabolism by regulating the actions of nitric oxide. Cell metabolism is the ongoing process of chemical transformations within the body's cells that sustains life, and alterations in metabolism are a common cause of human disease, including cancer and heart disease. Their findings about the mechanisms of action for coenzyme A, as well as discovering a new class of enzymes that regulate coenzyme A-based reactions, appear in the Dec. 15 edition of the Proceedings of the National Academy of Sciences (PNAS).