Researchers use gold substrate to allow for electron cryomicroscopy on difficult proteins

Friday, December 12, 2014 - 11:00 in Physics & Chemistry

(Phys.org)—A pair of researchers with the Medical Research Council Laboratory of Molecular Biology at the University of Cambridge in the U.K. has found a way to overcome the problem of movement by many proteins when attempting to study them using electron cryomicroscopy. In their paper published in the journal Science, Christopher Russo and Lori Passmore describe how they created a support structure based on a gold substrate that appears to solve the problem.

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