Protein-engineered cages aid studies of cell functions

Carbon monoxide (CO) plays an important role in cell functions, by signalling responses that counteract inflammation, and cell growth and death. As a result, researchers have been in pursuit of molecules that release CO into cells in order to study biological responses. Now Takafumi Ueno and colleagues in Japan report in the Journal of the American Chemistry Society how they have developed a protein cage that overcomes the limitations of previously reported CO releasing molecules.

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