It's not always the DNA: Damaged messenger RNA can jam cellular machines that make protein
Thursday, November 13, 2014 - 12:00
in Biology & Nature
Damage to DNA is an issue for all cells, particularly in cancer, where the mechanisms that repair damage typically fail. The same agents that damage DNA also damage its sister molecule messenger RNA (mRNA), which ferries transcripts of the genes to the tens of thousands of ribosomes in each cell. But little attention has been paid to this damage.